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SAMANTHA WHO? - "Samantha Who?" stars Christina Applegate as Samantha, Jennifer Esposito as Andrea, Kevin Dunn as Howard, Melissa McCarthy as Dena, Tim Russ as Frank with Barry Watson as Todd and Jean Smart as Regina. (ABC/BOB D'AMICO) BARRY WATSON, MELISSA McCARTHY, TIM RUSS, CHRISTINA APPLEGATE, JENNIFER ESPOSITO, JEAN SMART, KEVIN DUNN