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GREY'S ANATOMY - "Take the Lead" - The Chief makes a career-changing decision that shocks Seattle Grace Hospital; Cristina and Owen try to find normalcy in their relationship; April continues to struggle in her new role; and the 5th year residents are given their first solo surgeries, only to find out that even the most routine procedures aren't always easy, on Grey's Anatomy, THURSDAY, SEPTEMBER 29 (9:00-10:02 p.m., ET) on the ABC Television Network. (ABC/RICHARD CARTWRIGHT) PATRICK DEMPSEY, ELLEN POMPEO